Valtrex is used for:

Treating shingles (herpes zoster), cold sores (fever blisters or herpes labialis), and treating, suppressing, or reducing transmission of genital herpes in patients with normal immune systems. It is also used to treat chickenpox in children and teenagers. It is also used to suppress genital herpes in patients with HIV infection. Valtrex is an antiviral. It works by stopping viral replication. However, Valtrex does not eliminate the virus; it is not a cure. When used as a suppressive therapy in patients with normal immune systems with genital herpes using safer sex practices, the risk of spreading the infections to others is reduced.

Do NOT use Valtrex if:

* you are allergic to any ingredient in Valtrex or to acyclovir Contact your doctor or health care provider right away if any of these apply to you.

Before using Valtrex:

Some medical conditions may interact with Valtrex . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you: * if you are pregnant, planning to become pregnant, or are breast-feeding * if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement * if you have allergies to medicines, foods, or other substances * if you have a stomach infection, liver problems, brain or nervous system problems, increased pressure in the brain, Alzheimer disease, brain blood vessel problems, muscle problems (eg, myasthenia gravis), or a history of seizures * if you have a history of severe or persistent diarrhea, skin sensitivity to the sun, low blood potassium levels, heart problems, irregular heartbeat (eg, QT prolongation), or if you have a family member with a history of irregular heartbeat * if you have a history of joint or tendon problems; rheumatoid arthritis; kidney problems or decreased kidney function; or heart, kidney, or lung transplant * if you take corticosteroids (eg, prednisone) or you participate in strenuous physical work or exercise Some MEDICINES MAY INTERACT with Valtrex . Tell your health care provider if you are taking any other medicines, especially any of the following: * Antiarrhythmics (eg, amiodarone, quinidine) because the risk of serious side effects, including irregular heartbeat, may be increased * Corticosteroids (eg, prednisone) because they may increase the risk of tendon problems * Diuretics (eg, furosemide, hydrochlorothiazide), metoclopramide, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), or probenecid because they may increase the risk of Valtrex 's side effects * Anticoagulants (eg, warfarin), antipsychotics (eg, clozapine), cyclosporine, methotrexate, monoamine oxidase inhibitors (MAOIs) (eg, phenelzine), serotonin norepinephrine reuptake inhibitors (SNRIs) (eg, duloxetine), sulfonylureas (eg, glyburide), theophylline, tizanidine, tricyclic antidepressants (eg, amitriptyline), or xanthines (eg, caffeine) because the risk of their side effects may be increased by Valtrex * Hydantoins (eg, phenytoin) or live oral typhoid vaccine because their effectiveness may be decreased by Valtrex This may not be a complete list of all interactions that may occur. Ask your health care provider if Valtrex may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Valtrex:

Use Valtrex as directed by your doctor. Check the label on the medicine for exact dosing instructions. * Take Valtrex by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation. * Drinking extra fluids while you are taking Valtrex is recommended. Check with your doctor for instructions. * To treat cold sores, chickenpox, shingles, or genital herpes, start treatment as soon as possible after your symptoms start. * If treating an acute outbreak, use Valtrex for the full course of treatment. Keep using it even if you feel better in a few days. * For suppressive therapy, Valtrex works best if it is taken at the same time each day. * If you miss a dose of Valtrex , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Ask your health care provider any questions you may have about how to use Valtrex .

Possible side effects of Valtrex:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome: Dizziness; headache; nausea; stomach pain; vomiting. Seek medical attention right away if any of these SEVERE side effects occur: Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); aggressive behavior; bloody or dark urine; change in the amount of urine produced; confusion; depression; fatigue; fever; hallucinations; joint pain; lower back pain; pale skin; painful menstrual periods; pinpoint bruises; seizures; severe abdominal pain; shaky movements; speech problems; swelling of the face, hands, feet, or entire body; unsteady movement; unusual bruising or bleeding from the nose or mouth; weakness; yellowing of the skin or eyes. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

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